The remainder is within the extracellular space as the Extracellular Fluid. The extracellular compartment is further divided into three subcompartments, which are the plasma, the interstitial, and the transcellular subcompartments. The main intravascular fluid in mammals is blood which is a complex fluid with elements of a suspension (blood cells), colloid(globulins) and solvent(glucose and ions).The average volume of plasma in the average (70kg) male is approximately 3liters.The volume of the intravascular lumen is regulated in part by hydrostatic pressure gradients,and by readsorbtion by the kidneys. Two-thirds of total body water is held within cells as Intracellular Fluid (ICF). The intracellular compartment consists of all the fluids inside cells whereas the extracellular compartment consists of all the fluids outside of cells. In the average male (70kg)human body, the interstitial space has approximately 11 liters of fluid. Exchange of water in the human body:The extracellular, in turn, is divided into three compartments: interstitial, transcellular (fluid serous cavities: abdominal and pleural) and intravascular (represented by blood plasma). This fluid is not static, but is continally being refreshed and recollected by lymphatic channels. Outside the plasma membrane the cell is continually bathed in interstitial fluid ,which is the immediate microenvironment that allows for movement of ions, proteins and nutrients across the cell barrier. Describe the intracellular and extracellular fluid compartments, including components of each and the respective portion of total body weight that each. Materials travel between cells and the plasma in capillaries through the IF. Blood plasma is the second part of the ECF. The interstitial fluid (IF) is part of the extracellular fluid (ECF) between the cells. The intracellular compartment contains on average about 28 liters of fluid, and under ordinary circumstances remains in osmotic equilibrium with the ECF.Įxtracellular fluid Extravascular compartment The intracellular fluid (ICF) is the fluid within cells. Intracellular fluid is found inside the bilayered plasma membrane, and is the matrix in which cellular organelles are suspended, and chemical reactions take place.
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